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Mechanics of Biological Tissues

The structure-function relationships of biological materials are critical to understating tissue development, function, disease, and therapy. We use custom-built devices to simultaneously study structure and mechanics of biological tissues.

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Structure-Function Relations in Articular Cartilage's Shear Properties

Articular cartilage (AC), a biological tissue that protects and lubricates joints, plays a critical role during healthy locomotion.  Ongoing work in the Cohen lab has been examining the spatially heterogeneous mechanical properties of this tissue using confocal rheology.  This technique allows us to simultaneously deform the tissue with a known stress and measure the local strain field.  From this information, we can calculate the local shear properties.

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